Showing posts with label anton petrov. Show all posts
Showing posts with label anton petrov. Show all posts

Sunday, December 29, 2024

The hidden history of life, viruses, covid, y-chromosome bottlenecks and more...

Ah well, no advice that I offer* to obstinate politicos, pundits or AI-inventors ever gets past the Cliché Protection Barrier that's established to firmly keep out any ideas (and I got a million of em) that are Not-Invented-Here. Should I take a hint and stay in my lane?


Naw. But one way to keep defending this incredible, miraculously creative, anomalous Enlightenment Civilization is to keep pointing out how wonderful science truly is! And hence...



== The Wonderful World of Nature and Biology! ==


First... some great sites:


Anton Petrov's science podcast is a favorite. (Though I occasionally catch some small error; it's half the fun!) This time: using micro black holes for energy purposes on EarthIzat familiar? Tis, if you read my eponymous novel Earth. And this happens almost exactly on the timeline I projected, for that story's dramatic arc. 


My friend - and 25-year host of the Closer to Truth sci-philosophy TV series - Robert Lawrence Kuhn - just published a comprehensive survey of theories of consciousness — A Landscape of Consciousness: Toward a Taxonomy of Explanations and Implications. A balanced survey of the core philosophical issue of our time. 


Drinking water directly from the air? A concept predicted in one of the Out of Time novelsBoondoggle by Tom Easton and Torion Oey, which will soon be published by Amazing Stories. Now a real life product!  



== Tracing the hidden history of life ==


Pretty big (though interpolative) news: “By studying the genomes of organisms that are alive today, scientists have determined that the last universal common ancestor (LUCA), the first organism that spawned all the life that exists today on Earth, emerged as early as 4.2 billion years ago.  Earth, for context, is around 4.5 billion years old. That means life first emerged when the planet was still practically a newborn.” 

Now, this assumes several things, like a reliably constant rate of mutation divergence in life’s genetic heritage. If verified, it suggests that Life pops up quickly when conditions permit, rendering that factor in the Drake Equation (still speculatively) close to “1”.

Moreover – "But what is really interesting is that it's clear it possessed an early immune system, showing that even by 4.2 billion years ago, our ancestor was engaging in an arms race with viruses."


How much of the evolution of biochemistry is lost to time? "We might never know exactly, but our research yielded an important piece of evidence: only eight new reactions, all reminiscent of common biochemical reactions, are needed to bridge geochemistry and biochemistry.”  


And yes, I expect the Drake factor f(L) to prove trivially large, as did f(P). Planets and life, everywhere... but f(i) very small and f(c) - true civilizations that escape the male reproductive strategy called feudalism, in order to become creative and civilized enough to reach the stars? Vanishingly small.



== But let's cheer up! ==


Much later… a stress event in the early Jurassic may have driven many bird-hipped and two-legged dinosaurs to higher latitudes where they had to develop feathers and warm-bloodedness to survive, while the poor lizard-hipper giants had to make do in more arid lands.  Yay bird-hippers! (And the furry little mammals who followed them into the hills.)


A hilarious and insightfully informative video - How Cats Broke the Game - that explores the biology and anthropology of humanity's partnership with cats... told entirely in GAMER PLAY terms, e.g. build-points and skill-sets and power-ups, terminology that winds up making surprisingly solid sense. In fact, it's new-gen speak that actually rather impressed me.  


(Though humans bred terriers and other dog types who are also great ratters. And much more loyal.)


And in news from deeper time… This particular posting by Anton Petrov is especially interesting, re the impudent proposal that complex (multicellular) life forms had a brief start during an oxygenization event around 2.1 billion years ago, only to die off, leaving only single celled life till at least a billion years later, when it got rolling again. Naturally, it seems slim... though without any killer refutations, so far. And... well... interesting!



 == Peering at human bottlenecks ==


New evidence indicates that humans left Africa earlier than thought.... "The Neanderthal Y chromosome, for example, is more similar to the Y chromosome found in living humans than it is to the rest of the Neanderthal genome. In 2020, researchers offered an explanation: Neanderthal males inherited a new Y chromosome from humans between 370,000 and 100,000 years ago. But that would have made sense only if a wave of Africans had expanded out of the continent much earlier than scientists had thought."


"But why do the early migrations out of Africa seem to have fizzled away? Was there something different about the people in the last wave?"


Well, yeah, I talk about it in Existence.


A more recent bio mystery that’s been discussed a lot right here, in this blog’s lively comment community (below) has been the Great Big Y-Chromosome Bottleneck, from about 7000 to 5000 years ago, which appears to have started – and ended – rather suddenly, especially From Europe to South Asia. This article describes it pretty well. 


But how do you get a situation in which nearly all healthy females got to breed, but only one male in 17? And why would it happen (and stop) all across Eurasia with such brutal suddenness?


My own theory. It began with the arrival of larger farming villages, in which old tribal democracy could no longer function. No longer hold local 'lordly' bullies in check. Not when those top bullies could gather an 'army' of 20+ pals, call themselves demigods and simply take the widows of any men they killed. (That era also coincides with the arrival of large scale beer brewing; ponder that.) 


And the Y-Chromosome Bottleneck ended just as quickly! Pretty much as soon as some of those large villages gathered into even larger town- and city-based kingdoms. Those bigger-scale kings -- from Ur to the Indus to the Nile -- needed law and order! They also needed men for their armies, in struggles against other big kings. And hence they would have commanded local lords to stop wholesale slaughter of other local men! 


Those events would fit the order and sequence of the chromosomal evidence perfectly! Though... yes... that is a long way from proof.


And further DNA sleuthing opens such a window into a Scandinavian village 5000 years ago, tracing seven generations of 100 related individuals, 17% of whom had… the Plague. Which may have accounted for population declines. Which leads us to…



== Preparing for the next pandemic? ==


I have yet to see a single person, even one, point out the real, topmost effect of the Covid-19 epidemic.  That it was a spectacularly effective and relatively mild wakeup call and training exercise, for when we must deal with the real thing. A real ‘pandemic.’


All of what I just said may offend those of you who lost one or more people to that nasty disease… or if you claim that both government and society bungled the response. True enough. Still, I am not deterred from calling em as I see em. 

For example, while millions died, when you factor in remaining lifespan (most fatalities were elderly), the number of lost human years doesn’t rank anywhere in the top rank of plagues. 


For example, when compared to the 1918 flu calamity. As related by Evan Anderson in a recent Strategic News Service report: “(The 1918 flu) was by far the worst thing that has ever happened to humankind; not even the Black Death of the Middle Ages comes close in the number of lives it took. A 1994 report by the World Health Organization pulled no punches. The 1918 pandemic, it said, "killed more people in less time than any other disease before or since." It was the "most deadly disease event in the history of humanity." - Albert Marrin, Very, Very, Very Dreadful: The Influenza Pandemic of 1918.

(Well… worst in total deaths, sure. Though not as a fraction of the population or in seismic effects upon civilization. But sure. way-way worse than anything we the living have seen.)


This is small comfort to those who lost loved ones, or who still suffer from Long Covid. (I know several and it’s a nasty syndrome that must be fought with science!) And I am well aware how consensus is shifting, re: the disease’s origins -- toward a verdict that this was no ‘accident.’ At least not completely. 

Still, I expect future generations will deem the whole episode to have been ‘innoculatory’… leaving us much better prepared for something truly worse. 


Like (perhaps) the H5N1 Bird Flu that’s now spreading among mammals, killing (for example) thousands of elephant seals and spreading through dairy and beef cattle*. With signs of seeping into pigs and thence maybe human-to-human… though let's emphasize that experts still rank it as ‘low risk.’


== More blessings from Covid-19? ==


A few – very few – have openly marveled over the incredible speed with which RNA-based vaccines arrived, saving millions and leading to even better/quicker skills. Stockpiles of medical supplies and apparatus are far improved and bureaucracies finer tuned. Even the mistakes that were made in the initial covid-panic led to better understanding. 


For example, next time we’ll likely know within mere days whether a pathogen can be transmitted by ‘fomites’, by non-living surfaces. So, no bleaching your store packages or produce, or microwaving your mail. Though hand washing proved-out as a very, very good thing.** And fer gosh sakes stay home with your sniffles and coughs!


Surveillance and detection, while at 1% of what experts say we should be funding, are at least a hundred-fold better than before, e.g. sampling viral loads in city waste water ‘sewersheds.’


Of course, none of this is helped by anti-science manias like the new U.S. Defense Secretary appointee, who proudly declared: "I don't believe in germs and I haven't washed my hands in a decade!" 

... or vaccine denialism by loons, who romanticize the 1950s as some whitebread paradise era, while ignoring the myriad ways that things were far more wretched then – and reasons why – during that decade, as I well recall – the most-adored person in America was named Jonas Salk


If science-haters truly carry out their open plans, we could be in big trouble (as described chillingly in these few paragraphs by Robert Heinlein). Or even if they remain the raving impediments that they currently are. 


None of this is meant to minimize. In fact, my job is to look ahead at possibilities, both bright and dark. And both future-view and history suggest 'pandemics' can get far, far worse than Covid-19. And while we are certainly unprepared, we are definitely less unprepared than we were.


(* Thorough cooking does kill the virus, so maybe rare steaks should be off the menu, for a while. Pasteurized milk seems to be fine.)


Then there’s this on the history of vaccines. 



== Final tidbits ==


‘Researchers have uncovered what might be the world’s oldest solar calendar at Göbekli Tepe, a 12,000-year-old archaeological site in southern Turkey.’  The implications of very pre-literate sophistication are so interesting.


Does putting Neosporin in your nose help fend off covid? Surprisingly, there’s preliminary evidence that it does. 



And finally this bit of genuine wisdom to cancel your incel rage junkie.... 

 

"He's just mad because he was abandoned by wolves and raised by his parents.                       

                          -- Robin Williams




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* Though again, Joe Biden has two weeks to do one thing


One thing easily within his power, that might shatter the worst madness, infection and treason among the US political and aristocratic castes. 


He could do this. He could... though his factotums will ensure that he won't.


Saturday, July 30, 2022

Some great science podcasts - tune in!

Couple of years back we offered a list of excellent – if sometimes specialized – podcasts and YouTube channels about science and related things. Time for an update?


== Great Science (and other) Podcasts! ==


Let’s start with Into the Impossible - hosted by my friend Dr. Brian Keating, co-director of UCSD's Arthur C. Clarke Center for Human Imagination. Generally a deep dive into aspects of physics, but also space biology, tech and the latest insights into the nature of imagination. Example video: What is Dark Matter?

A colleague of Brian's whom I also admire: Dr. Sabine Hossenfelder -- Science and technology updates - "without the gobbledygook". Example video: Are Singularities Real?

As I said then… Scott Manley is one of my favorite YouTube explainer guys, especially when it comes to spacecraft. If there's some kind of milestone in rocketry, for example, he'll clarify it for you, within a couple of days. (Manley was also designer of the "cycler" spacecraft in the 2021 movie "Stowaway".) But this particular posting goes a bit farther in space and especially time, as Manley  talks about how to Move the Earth, citing especially my own postings on the subject.


Other favorite explainers include Anton Petrov for well-delivered and timely updates on the latest science and space discoveries, starting each with "Hello Wonderful Person!" Example video: James Webb Just found the most distant galaxy


Dianna Cowern, Physics Girl, presents  physical science demonstrations, experiments and explanations of new discoveries. Example video: We were wrong about the Big Bang.


Science & Futurism with Isaac Arthur provides in-depth explorations of galactic stuff like the Fermi Paradox. If it involves space and destiny, you can bet he's got an engaging what-if riff. Example video: Black holes & Dark Matter.


A pal of Isaac (and me) is John Michael Godier's Event Horizon, whose podcasts are a little closer to Earth than Arthur's, but still vividly entertaining futurism, featuring great interviews. How do I know this? Example video: What's eating the Universe?


== A golden age of Chatauqua explainers? ==


Fools and feudalists who try to diss the high repute of science, calling it just another orthodoxy, know nothing about the impudent competitiveness taught to most bright graduate students, along with the central catechism of science: "I might be wrong!" No other 'priesthood' ever even remotely did that. Nor spawned the phenomenon displayed here... of so many top researchers and experts rushing onto PBS or podcasts to eagerly share everything they've learned... and address every unanswered question!


Here are more! Including some favorites offered by other folks.


Dr. Becky Smethurst (Dr. Becky) -- A day in the life of an Astrophysicist at Oxford, with a focus on astronomy and cosmology research. Example video: An Astrophysicist's Top 10 Unsolved Mysteries.


Mark Rober, former NASA engineer, produces videos on popular science and gadgets, as well as science-related pranks, with over 22 million subscribers. Example video: World's Tallest Elephant Toothpaste Volcano. (Note Rober is hugely popular with young folks.)

Jade Tan-Holmes (Up and Atom) -- Kids level explanations of high-end physics concepts. Example video: What is The Schrodinger Equation, Exactly?

Steve Mould -- Mix of science/engineering topics. Example video: Pythagorean Siphon - Inside Your Washing Machine

Amy Shira Teitel, The Vintage Space -- History of the space program, branching into "How it works" on related subjects. Example video: Vladimir Komarov was Doomed to Die on Soyuz 1.

Prof. David Kipping (Cool Worlds) -- Great selection of topics. Okay the presentation can ponderous. Why You're Probably Not a Simulation.


Kurzgesagt -- Distinctively animated videos on science/space topics.  Example video: The Day the Dinosaurs Died - Minute by Minute.

Brew -- Animated videos on a variety of subjects, with an extra serving of body horror. Example video: The Country Made from 14 Stranded Ships.

Dr. Rohin Francis (Medlife Crisis) -- Cardiologist with an acidic sense of humour.
Example video: Can You Legally Buy a Real Human Skeleton.

Johnny Harris -- Deeper dives into specific odd subjects. Non-political example: The Real Reason McDonalds Ice Cream Machines Are Always Broken (Except everything is political.)

Joe Scott (Answers With Joe) -- Wide variety of topics, often science/space/tech focused: The Immortal Woman Who Saved Millions Of Lives"

Tom Scott -- Variety of subjects, from "this is an interesting place that exists", to linguistics, to infotech, to very random projects that catch his interest. 
Interesting place: The Artificial Gravity Lab.
Infotech: This Video Has 32,251,959 Views (title subject to change.)
Language: The Language Sounds That Could Exist But Don't.


Derek Muller (Veritasium). Science and engineering videos. Example video: Fritz Haber: the scientist who killed millions but saved billions.
 
Tim Dodd (Everyday Astronaut). Bringing space down to earth for everyday people, with updates on rockets and space launches. Example video: Raptor 1 vs Raptor 2: What's the difference?

Destin Sandlin (Smarter Every Day) explores the everyday world using science. Example: How do nuclear submarines make oxygen?
 
PBS Spacetime: Our Universe Explained, with Dr. Matt O'Dowd - is the best in my opinion. Example video: The Edge of an Infinite Universe.



== Terrific Miscellaneous ones... and sci fi! ==


Savor Podcast delves into the science, history and cultural connections of food and drink: why exactly we like what we like. Example podcast: Fictional Foods: Doctor Who.


This science fiction insight podcast had a short run, but is fabulous. 


A couple of political-historical channels that I think have been mentioned here:


The History Guy: History that deserves to be remembered. Forgotten moments of history presented in an entertaining manner.

Beau of the Fifth Column -- Lefty perspective made in the style of a right-winger.

Cody Johnston (Some More News) -- Lefty perspective made in the style of... errr, a crazy basement dweller trying to drag you down with him?


And to balance that... Bill Maher. yes, I said it. If no one will listen to my advice how the Union side of our civil war can win with innovative tactics, then at least pay attention when Maher chides you to stop deliberately losing with abysmally stoopid ones. 


Quirky (and stylistically immature, but a bit fun) perspectives on military matters, including the Ukraine War: Task & Purpose.

And I'll throw in English GP Dr. John Campbell, who is doing quiet daily Covid-19 updates.


Don't forget!! You can support these podcasters and content creators by subscribing - as well as donating on Patreon and via YouTube's new SuperThanks feature.


And for more, check comments, below! There will be many suggestions by members of this community!


What an amazing era we live in.